Multiple sclerosis functional composite
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The Multiple Sclerosis Functional Composite (MSFC) is a clinical trial outcome measure of assessing the severity of multiple sclerosis primarily used in research.[1] The score is based on a combination of timed tests of walking, arm function, and cognitive ability.[1] It was developed over two years from 1994 to 1996 by the National Multiple Sclerosis Society.[1][2]
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MSFC was developed to improve the standard measure of MS disability for clinical trials and to create a multidimensional metric of overall MS clinical status. The evaluation includes a three-part performance scale:
- Timed 25-Foot Walk (T25FT) - assessment of leg function by moving a short walking distance
- 9-Hole Peg Test (9HPT) - assessment of arm function using breadboard test
- Paced Auditory Serial Addition test (PASAT) - attention/concentration test to assess cognitive functions
References
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