Muscavirus

Muscavirus is a genus of viruses, in the family Hytrosaviridae.^[1] The fly Musca domestica is the natural host. There is only one species in this genus: Musca domestica salivary gland hypertrophy virus (Muscavirus musdomesticae). Diseases associated with this genus include: salivary gland hypertrophy, and complete sterility of infected female flies by inhibiting eggs development.^[2][3][4]

Muscavirus
Virus classification
(unranked):	Virus
Class:	Naldaviricetes
Order:	Lefavirales
Family:	Hytrosaviridae
Genus:	Muscavirus

Structure

Viruses in the genus Muscavirus are enveloped, with rod-shaped geometries. The diameter is around 50 nm. Genomes are circular, around 124kb in length. The genome has 108 open reading frames.^[2][3]

Genus	Structure	Symmetry	Capsid	Genomic arrangement	Genomic segmentation
Muscavirus	Rod-shaped		Enveloped	Circular	Monopartite

Life cycle

Viral replication is nuclear. DNA-templated transcription is the method of transcription. Musca domestica serve as the natural host. Transmission routes are parental and contamination.^[2][3]

Genus	Host details	Tissue tropism	Entry details	Release details	Replication site	Assembly site	Transmission
Muscavirus	Insects: house flies	Epithelium: secretory salivary glands; ovarioles; gonads	Contact: food; horizontal; vertical	Budding; horizontal; vertical	Nucleus	Nucleus	Contact: food; horizontal; vertical