NF-kappa-B-activating protein

NF-kappa-B-activating protein is a protein that in humans is encoded by the NKAP gene.^[5][6]

NKAP
Identifiers
Aliases	NKAP, NFKB activating protein, MRXSHD
External IDs	OMIM: 300766; MGI: 1914300; HomoloGene: 134325; GeneCards: NKAP; OMA:NKAP - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq24 Start 119,920,672 bp[1] End 119,943,751 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A3.3 Start 36,390,448 bp[2] End 36,414,399 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon sural nerve gonad monocyte buccal mucosa cell gastrocnemius muscle C1 segment muscle of thigh right adrenal cortex left adrenal gland Top expressed in aortic valve otic placode ascending aorta fossa otic vesicle substantia nigra external carotid artery internal carotid artery condyle supraoptic nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function chromatin DNA binding protein binding RNA binding chromatin binding Cellular component nucleus nucleoplasm cytosol Biological process Notch signaling pathway stem cell population maintenance hematopoietic stem cell proliferation hemopoiesis granulocyte differentiation negative regulation of transcription by RNA polymerase II T cell differentiation in thymus positive regulation of alpha-beta T cell differentiation regulation of transcription, DNA-templated transcription, DNA-templated positive regulation of protein targeting to mitochondrion negative regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79576 67050 Ensembl ENSG00000101882 ENSMUSG00000016409 UniProt Q8N5F7 Q9D0F4 RefSeq (mRNA) NM_024528 NM_025937 RefSeq (protein) NP_078804 NP_080213 Location (UCSC) Chr X: 119.92 – 119.94 Mb Chr X: 36.39 – 36.41 Mb PubMed search [3] [4]
Wikidata
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