Neuropeptide FF receptor 2

Neuropeptide FF receptor 2, also known as NPFF2 is a human protein encoded by the NPFFR2 gene.^[5]

NPFFR2
Identifiers
Aliases	NPFFR2, GPR74, HLWAR77, NPFF2, NPGPR, neuropeptide FF receptor 2
External IDs	OMIM: 607449; MGI: 1860130; HomoloGene: 56982; GeneCards: NPFFR2; OMA:NPFFR2 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q13.3 Start 72,031,902 bp[1] End 72,148,305 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 E1 Start 89,675,288 bp[2] End 89,731,599 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad testicle placenta islet of Langerhans prefrontal cortex parietal pleura gastric mucosa seminal vesicula Brodmann area 9 appendix Top expressed in primary oocyte zygote secondary oocyte embryo spinal ganglia blastocyst olfactory bulb mandibular prominence testicle trigeminal ganglion More reference expression data BioGPS n/a
Gene ontology Molecular function opioid receptor binding peptide binding G protein-coupled receptor activity signal transducer activity neuropeptide receptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane actin cytoskeleton Biological process G protein-coupled receptor signaling pathway detection of abiotic stimulus cellular response to hormone stimulus regulation of MAPK cascade regulation of adenylate cyclase activity regulation of cAMP-dependent protein kinase activity signal transduction response to peptide neuropeptide signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10886 104443 Ensembl ENSG00000056291 ENSMUSG00000035528 UniProt Q9Y5X5 Q924H0 RefSeq (mRNA) NM_001144756 NM_004885 NM_053036 NM_133192 RefSeq (protein) NP_001138228 NP_004876 NP_444264 NP_573455 Location (UCSC) Chr 4: 72.03 – 72.15 Mb Chr 5: 89.68 – 89.73 Mb PubMed search [3] [4]
Wikidata
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See also

• Neuropeptide FF receptor