Nucleoporin 155

Nucleoporin 155 (Nup155) is a protein that in humans is encoded by the NUP155 gene.^[5][6]

NUP155
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5A9Q, 5IJN, 5IJO
Identifiers
Aliases	NUP155, ATFB15, N155, nucleoporin 155kDa, nucleoporin 155
External IDs	OMIM: 606694; MGI: 2181182; HomoloGene: 43155; GeneCards: NUP155; OMA:NUP155 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p13.2 Start 37,288,137 bp[1] End 37,371,106 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 A1 Start 8,138,757 bp[2] End 8,190,731 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm left testis right testis secondary oocyte gonad testicle ventricular zone Achilles tendon embryo ganglionic eminence Top expressed in tail of embryo epiblast spermatocyte genital tubercle internal carotid artery external carotid artery maxillary prominence mandibular prominence pineal gland cumulus cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transporter activity protein binding structural constituent of nuclear pore Cellular component nuclear membrane membrane nuclear envelope nuclear pore nucleus nuclear pore inner ring host cell Biological process mRNA transport nuclear envelope organization viral transcription protein sumoylation mitotic nuclear membrane disassembly nucleocytoplasmic transport atrial cardiac muscle cell action potential regulation of cellular response to heat protein transport viral process intracellular transport of virus protein import into nucleus RNA export from nucleus tRNA export from nucleus transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery protein localization to nuclear inner membrane mRNA export from nucleus regulation of gene silencing by miRNA regulation of glycolytic process transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9631 170762 Ensembl ENSG00000113569 ENSMUSG00000022142 UniProt O75694 Q99P88 RefSeq (mRNA) NM_001278312 NM_004298 NM_153485 NM_133227 RefSeq (protein) NP_001265241 NP_004289 NP_705618 NP_573490 Location (UCSC) Chr 5: 37.29 – 37.37 Mb Chr 15: 8.14 – 8.19 Mb PubMed search [3] [4]
Wikidata
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Nucleoporins are the main components of the nuclear pore complex (NPC) of eukaryotic cells. They are involved in the bidirectional trafficking of molecules, especially mRNAs and proteins, between the nucleus and the cytoplasm. The protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. Two protein isoforms are encoded by transcript variants of this gene.^[6]

Interactions

NUP155 has been shown to interact with GLE1L.^[7]