Nucleoporin 35

Nucleoporin 35 (Nup35) is a protein that in humans is encoded by the NUP35 gene.^[5]

NUP35
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4LIR
Identifiers
Aliases	NUP35, MP-44, MP44, NP44, NUP53, nucleoporin 35kDa, nucleoporin 35
External IDs	OMIM: 608140; MGI: 1916732; HomoloGene: 44517; GeneCards: NUP35; OMA:NUP35 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q32.1 Start 183,117,513 bp[1] End 183,161,680 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 C3 Start 80,447,580 bp[2] End 80,489,250 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte sperm ventricular zone pancreatic epithelial cell gonad Achilles tendon cartilage tissue islet of Langerhans ganglionic eminence Top expressed in secondary oocyte zygote primary oocyte morula yolk sac epiblast tail of embryo genital tubercle embryo embryo More reference expression data BioGPS n/a
Gene ontology Molecular function single-stranded DNA binding protein binding phospholipid binding nucleic acid binding structural constituent of nuclear pore Cellular component nuclear lamina nuclear membrane nuclear envelope membrane plasma membrane nuclear pore nucleoplasm nuclear pore central transport channel nuclear pore nuclear basket nucleus host cell Biological process mRNA transport regulation of transcription, DNA-templated protein transport viral process nuclear pore organization NLS-bearing protein import into nucleus mRNA export from nucleus nucleocytoplasmic transport regulation of glycolytic process tRNA export from nucleus protein sumoylation viral transcription regulation of gene silencing by miRNA intracellular transport of virus regulation of cellular response to heat Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 129401 69482 Ensembl ENSG00000163002 ENSMUSG00000026999 UniProt Q8NFH5 Q8R4R6 RefSeq (mRNA) NM_001008544 NM_001287584 NM_001287585 NM_138285 NM_001190179 NM_027091 RefSeq (protein) NP_001274513 NP_001274514 NP_612142 NP_001177108 NP_081367 Location (UCSC) Chr 2: 183.12 – 183.16 Mb Chr 2: 80.45 – 80.49 Mb PubMed search [3] [4]
Wikidata
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Background

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.^[5]