Nelremagpran

Nelremagpran is an experimental drug that acts as a potent and selective antagonist (or possibly inverse agonist) of the MAS-related Gq protein-coupled receptor X4 (MRGPRX4). It has antiinflammatory effects in animal studies. This receptor is poorly characterised but is thought to be involved in immune system function, and development of selective ligands is essential for researching its role in the body.^[1][2]

Nelremagpran

Identifiers
IUPAC name 3-[[2-chloro-4-(trifluoromethyl)phenoxy]methyl]-2-fluorobenzoic acid
CAS Number	2492595-24-9
PubChem CID	155145968
ChemSpider	115008493
UNII	BL83FAK6DZ
ChEMBL	ChEMBL4855031
Chemical and physical data
Formula	C15H9ClF4O3
Molar mass	348.68 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC(=C(C(=C1)C(=O)O)F)COC2=C(C=C(C=C2)C(F)(F)F)Cl
InChI InChI=1S/C15H9ClF4O3/c16-11-6-9(15(18,19)20)4-5-12(11)23-7-8-2-1-3-10(13(8)17)14(21)22/h1-6H,7H2,(H,21,22) Key:TWOXPNAILYKJPT-UHFFFAOYSA-N