Neramexane

Neramexane
Clinical data
ATC code	none;
Identifiers
	IUPAC name 1,3,3,5,5-pentamethylcyclohexanamine;
CAS Number	219810-59-0 ;
PubChem CID	6433106;
ChemSpider	4938294 ;
UNII	856DX0KJ84;
CompTox Dashboard (EPA)	DTXSID40176399 ;
ECHA InfoCard	100.107.752
Chemical and physical data
Formula	C11H23N
Molar mass	169.312 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(C)(N)CC(C)(C)CC(C)(C)C1;
	InChI InChI=1S/C11H23N/c1-9(2)6-10(3,4)8-11(5,12)7-9/h6-8,12H2,1-5H3 ; Key:OGZQTTHDGQBLBT-UHFFFAOYSA-N ;
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Neramexane is a drug related to memantine,^[1] which acts as an NMDA antagonist^[2] and has neuroprotective effects.^[3] It is being developed for various possible applications, including treatment of tinnitus,^[4]^[5] Alzheimer's disease,^[6] drug addiction^[7] and as an analgesic.^[8] Animal studies have also suggested antidepressant^[9] and nootropic^[10] actions so that this drug may be used for a wide range of potential applications. It also acts as a nicotinic acetylcholine receptor antagonist.^[11]

Quick Facts Clinical data, ATC code ...

A clinical trial found that doses of 50 mg and above safely improved tinnitus scores over 16 weeks.^[12]

See also