NiCo riboswitch

The NiCo riboswitch is a riboswitch that senses nickel or cobalt ions.^[1] Thus, it is an RNA molecule that specifically binds these metal ions, and regulates genes accordingly. The riboswitch is thought to be a part of a system that responds to toxic levels of these metal ions, although the riboswitch might also participate in dealing with the situation where insufficient levels of these trace elements are present in the cell.^[1] The crystal structure of a NiCo riboswitch has been determined, and available evidence suggests that the riboswitches bind their metal-ion ligands cooperatively.^[1]

NiCo-AnGGAG
Consensus secondary structure and sequence conservation of NiCo-AnGGAG riboswitch
Identifiers
Symbol	NiCo-AnGGAG
Rfam	RF03164
Other data
RNA type	Cis-reg
GO	GO:0046872
SO	SO:0000035
PDB structures	PDBe