Nifenazone

Nifenazone is a drug that has been used as an analgesic for a number of rheumatic conditions.^[1]

Nifenazone

Clinical data
ATC code	M02AA24 (WHO) N02BB05 (WHO)
Identifiers
IUPAC name N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)nicotinamide
CAS Number	2139-47-1 Y
PubChem CID	4487
ChemSpider	4332 Y
UNII	8780F0K71U
KEGG	D01437 Y
ChEMBL	ChEMBL1413176 Y
CompTox Dashboard (EPA)	DTXSID7045366
ECHA InfoCard	100.016.716
Chemical and physical data
Formula	C17H16N4O2
Molar mass	308.341 g·mol−1
3D model (JSmol)	Interactive image
SMILES c1ccccc1N2N(C)C(C)=C(C2=O)NC(=O)c3cccnc3
InChI InChI=1S/C17H16N4O2/c1-12-15(19-16(22)13-7-6-10-18-11-13)17(23)21(20(12)2)14-8-4-3-5-9-14/h3-11H,1-2H3,(H,19,22) Y Key:BRZANEXCSZCZCI-UHFFFAOYSA-N Y

Synthesis

Nifenazone is the amide formed when ampyrone and the acid chloride of nicotinic acid are combined in a Schotten–Baumann reaction.^[2][3]

See also

• Aminopyrine