Norpipanone

Norpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina, and other countries.^[2][3] It had originally not been under international control but upon observation of case reports of addiction it was reviewed and shortly thereafter became a controlled substance.^[2][3] In the United States, it is a Schedule I controlled substance (ACSCN 9636, zero annual manufacturing quota as of 2014). The salts in use are the hydrobromide (free base conversion ratio 0.806) and hydrochloride (0.902).

Norpipanone

Clinical data
Other names	Herchst 10495, NIH-7557
ATC code	None
Legal status
Legal status	AU: S9 (Prohibited substance) BR: Class A1 (Narcotic drugs)[1] CA: Schedule I DE: Anlage I (Authorized scientific use only) US: Schedule I
Identifiers
IUPAC name 4,4-diphenyl-6-(1-piperidinyl)-3-hexanone
CAS Number	561-48-8
PubChem CID	22391
ChemSpider	21015
UNII	127X8DJ74M
KEGG	D12701 Y
CompTox Dashboard (EPA)	DTXSID60204643
ECHA InfoCard	100.008.383
Chemical and physical data
Formula	C23H29NO
Molar mass	335.491 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(C(c1ccccc1)(c2ccccc2)CCN3CCCCC3)CC
InChI InChI=1S/C23H29NO/c1-2-22(25)23(20-12-6-3-7-13-20,21-14-8-4-9-15-21)16-19-24-17-10-5-11-18-24/h3-4,6-9,12-15H,2,5,10-11,16-19H2,1H3 Key:WCDSHELZWCOTMI-UHFFFAOYSA-N

Synthesis

Norpipanone synthesis:^[4][5]

See also

• Dipipanone
• Normethadone