Odorant-binding protein 2A

Odorant-binding protein 2a is a protein that in humans is encoded by the OBP2A gene.^[5]

OBP2A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4RUN
Identifiers
Aliases	OBP2A, LCN13, OBP, OBP2C, OBPIIa, hOBPIIa, odorant binding protein 2A
External IDs	OMIM: 164320; MGI: 3651927; HomoloGene: 135821; GeneCards: OBP2A; OMA:OBP2A - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q34.3 Start 135,546,126 bp[1] End 135,549,969 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 25,627,021 bp[2] End 25,630,109 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube skin of leg caput epididymis skin of abdomen testicle right testis left testis bone placenta bone marrow Top expressed in embryo hypothalamus striatum of neuraxis olfactory bulb pancreas islet of Langerhans dentate gyrus of hippocampal formation granule cell Cortex of frontal lobe superior frontal gyrus thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function odorant binding small molecule binding Cellular component extracellular region cellular component Biological process sensory perception of chemical stimulus sensory perception of smell response to stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29991 383678 Ensembl ENSG00000122136 ENSMUSG00000079539 UniProt Q9NY56 A2BHR0 RefSeq (mRNA) NM_001293189 NM_001293193 NM_014582 NM_001099301 NM_001378280 RefSeq (protein) NP_001280118 NP_001280122 NP_055397 NP_001365209 Location (UCSC) Chr 9: 135.55 – 135.55 Mb Chr 2: 25.63 – 25.63 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a small extracellular protein belonging to the lipocalin superfamily. The protein is thought to transport small, hydrophobic, volatile molecules or odorants through the nasal mucus to olfactory receptors, and may also function as a scavenger of highly concentrated or toxic odors. The protein is expressed as a monomer in the nasal mucus, and can bind diverse types of odorants with a higher affinity for aldehydes and fatty acids. This gene and a highly similar family member are located in a cluster of lipocalin genes on chromosome 9. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.^[5]