Opioidergic

An opioidergic agent (or drug) is a chemical which directly or indirectly modulate the function of opioid receptors. Opioidergics comprise opioids, as well as allosteric modulators and enzyme affecting agents like enkephalinase inhibitors.

Structural correlation between met-enkephalin, an opioid peptide, (left) and morphine, an opiate drug, (right)

Allosteric modulators

BMS-986121

• BMS-986121: μ-PAM^[1]
• BMS-986122: μ-PAM^[1]
• BPRMU191: confers agonistic properties to small-molecule morphinan antagonists^[2]
• Ignavine^[3]
• Oxytocin: μ-PAM^[4]
• δ-PAM (see reference)^[5]
• Cannabidiol^[6]
• Tetrahydrocannabinol^[6]
• Sodium (Na⁺) ^[7]

See also

• List of opioids
• Adenosinergic
• Adrenergic
• Cannabinoidergic
• Cholinergic
• Dopaminergic
• GABAergic
• Glycinergic
• Histaminergic
• Melatonergic
• Monoaminergic
• Serotonergic