Oxolamine

Oxolamine is a cough suppressant^[1] that is available as a generic drug in many jurisdictions.^[2]

Oxolamine

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	R05DB07 (WHO)
Identifiers
IUPAC name N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine
CAS Number	959-14-8 Y
PubChem CID	13738
DrugBank	DB13216 Y
ChemSpider	13143 Y
UNII	90BEA145GY
KEGG	D07387 Y
ChEMBL	ChEMBL1620875 N
CompTox Dashboard (EPA)	DTXSID5023403
ECHA InfoCard	100.012.267
Chemical and physical data
Formula	C14H19N3O
Molar mass	245.326 g·mol−1
3D model (JSmol)	Interactive image
SMILES n1c(onc1c2ccccc2)CCN(CC)CC
InChI InChI=1S/C14H19N3O/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3 Y Key:IDCHQQSVJAAUQQ-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Oxolamine also has anti-inflammatory activity, which causes a reduction in irritation of the nerve receptors of the respiratory tract.^[3]

It is mainly used for the treatment of pharyngitis, tracheitis, bronchitis, bronchiectasis and pertussis.^[3]

Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant. It is listed as a prescription drug in New Zealand legislation. Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflammation.^[4]