Oxolinic acid

Oxolinic acid is a quinolone antibiotic developed in Japan in the 1970s.^[1][2] Dosages 12–20 mg/kg orally administered for five to ten days. The antibiotic works by inhibiting the enzyme DNA gyrase. It also acts as a dopamine reuptake inhibitor and has stimulant effects in mice.^[3]

Oxolinic acid

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J01MB05 (WHO)
Identifiers
IUPAC name 5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline- 7-carboxylic acid
CAS Number	14698-29-4 Y
PubChem CID	4628
ChemSpider	4467 N
UNII	L0A22B22FT
KEGG	D02301 N
ChEBI	CHEBI:138856 N
ChEMBL	ChEMBL416755 N
CompTox Dashboard (EPA)	DTXSID1021089
ECHA InfoCard	100.035.213
Chemical and physical data
Formula	C13H11NO5
Molar mass	261.233 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O
InChI InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17) N Key:KYGZCKSPAKDVKC-UHFFFAOYSA-N N
NY (what is this?)  (verify)

See also

• Amfonelic acid
• Fluoroquinolone