Phosphoglucomutase 3

Phosphoacetylglucosamine mutase is an enzyme that in humans is encoded by the PGM3 gene.^[5][6][7]

PGM3
Identifiers
Aliases	PGM3, AGM1, IMD23, PAGM, PGM 3, Phosphoglucomutase 3
External IDs	OMIM: 172100; MGI: 97566; HomoloGene: 9205; GeneCards: PGM3; OMA:PGM3 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q14.1 Start 83,161,150 bp[1] End 83,193,936 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 E3.1|9 46.58 cM Start 86,436,430 bp[2] End 86,453,895 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas islet of Langerhans stromal cell of endometrium anterior pituitary Achilles tendon cartilage tissue gonad left ovary sperm minor salivary glands Top expressed in epithelium of small intestine seminal vesicula umbilical cord yolk sac otolith organ utricle islet of Langerhans proximal tubule hand Paneth cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function intramolecular transferase activity, phosphotransferases phosphoglucomutase activity isomerase activity magnesium ion binding metal ion binding phosphoacetylglucosamine mutase activity Cellular component cytosol cellular component Biological process UDP-N-acetylglucosamine biosynthetic process protein O-linked glycosylation glucosamine metabolic process protein N-linked glycosylation glucose 1-phosphate metabolic process organic substance metabolic process spermatogenesis carbohydrate metabolic process hemopoiesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5238 109785 Ensembl ENSG00000013375 ENSMUSG00000056131 UniProt O95394 Q9CYR6 RefSeq (mRNA) NM_001199917 NM_001199918 NM_001199919 NM_015599 NM_001367286 NM_001367287 NM_001163746 NM_028352 RefSeq (protein) NP_001186846 NP_001186847 NP_001186848 NP_056414 NP_001354215 NP_001354216 NP_001157218 NP_082628 Location (UCSC) Chr 6: 83.16 – 83.19 Mb Chr 9: 86.44 – 86.45 Mb PubMed search [3] [4]
Wikidata
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Clinical significance

Mutations in PGM3 are associated to congenital disorder of glycosylation.^[8]