Plexin A1

Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene.^[5][6]

PLXNA1
Identifiers
Aliases	PLXNA1, NOV, NOVP, PLEXIN-A1, PLXN1, Plexin A1
External IDs	OMIM: 601055; MGI: 107685; HomoloGene: 56426; GeneCards: PLXNA1; OMA:PLXNA1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q21.3 Start 126,982,693 bp[1] End 127,037,389 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 D1 Start 89,293,296 bp[2] End 89,339,602 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus stromal cell of endometrium Brodmann area 23 endothelial cell sural nerve gingival epithelium Brodmann area 46 superior frontal gyrus Region I of hippocampus proper orbitofrontal cortex Top expressed in genital tubercle tail of embryo bronchus lobar bronchus lip dentate gyrus of hippocampal formation granule cell ascending aorta secondary oocyte primary visual cortex internal carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function semaphorin receptor activity signaling receptor activity Cellular component integral component of membrane membrane plasma membrane semaphorin receptor complex extracellular exosome integral component of plasma membrane Biological process regulation of axon extension involved in axon guidance neuron projection extension multicellular organism development neuron projection guidance branchiomotor neuron axon guidance dichotomous subdivision of terminal units involved in salivary gland branching regulation of smooth muscle cell migration semaphorin-plexin signaling pathway signal transduction negative regulation of cell adhesion regulation of cell shape regulation of cell migration regulation of GTPase activity positive regulation of axonogenesis semaphorin-plexin signaling pathway involved in axon guidance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5361 18844 Ensembl ENSG00000114554 ENSMUSG00000030084 UniProt Q9UIW2 P70206 RefSeq (mRNA) NM_032242 NM_008881 RefSeq (protein) NP_115618 NP_032907 Location (UCSC) Chr 3: 126.98 – 127.04 Mb Chr 6: 89.29 – 89.34 Mb PubMed search [3] [4]
Wikidata
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Interactions

Plexin A1 has been shown to interact with AKT1.^[7]