Paradoxin

Paradoxin (PDX) is a presynaptic neurotoxic phospholipase found in the venom of the inland taipan (Oxyuranus microlepidotus), an extremely venomous species of snake native to Australia.^[1]

The Inland taipan produces paradoxin in its venom

Structure

It is similar in structure to another neurotoxin named Taipoxin. However they differ in how they are neurotoxic. It is a heterotrimer and composed of three subunits.^[2][3]

Toxicity

Relatively little is known about paradoxin including its neuromuscular activity.^[1] It is known that paradoxin blocks nerve impulses in the synapses by disrupting and blocking neuromuscular transmission.^[4]