Pentachlorophenol monooxygenase

Pentachlorophenol monooxygenase (EC 1.14.13.50, pentachlorophenol dechlorinase, pentachlorophenol dehalogenase, pentachlorophenol 4-monooxygenase, PCP hydroxylase, pentachlorophenol hydroxylase, PcpB, PCB 4-monooxygenase, PCB4MO) is an enzyme with systematic name pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating).^{[1][2][3][4][5]} This enzyme catalyses the following chemical reaction

(1) pentachlorophenol + 2 NADPH + H⁺ + O2 ${\displaystyle \rightleftharpoons }$ 2,3,5,6-tetrachlorohydroquinone + 2 NADP⁺ + chloride + H₂O

(2) 2,3,5,6-tetrachlorophenol + NADPH + H⁺ + O2 ${\displaystyle \rightleftharpoons }$ 2,3,5,6-tetrachlorohydroquinone + NADP⁺ + H₂O

Pentachlorophenol monooxygenase
Identifiers
EC no.	1.14.13.50
CAS no.	136111-57-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Pentachlorophenol monooxygenase is a flavoprotein (FAD).