Perflubron

Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography.^[1] It was approved for this use in the United States by the Food and Drug Administration in 1993.^[2]

Perflubron

Clinical data
ATC code	V08CX01 (WHO)
Identifiers
IUPAC name 1-Bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
CAS Number	423-55-2
PubChem CID	9873
ChemSpider	9489
UNII	Q1D0Q7R4D9
ChEMBL	ChEMBL1200866
CompTox Dashboard (EPA)	DTXSID5046560
ECHA InfoCard	100.006.391
Chemical and physical data
Formula	C8BrF17
Molar mass	498.965 g·mol−1
3D model (JSmol)	Interactive image
Density	1.93 g/cm3
Melting point	6 °C (43 °F)
Boiling point	142 °C (288 °F)
SMILES FC(F)(C(F)(F)C(Br)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26 Key:WTWWXOGTJWMJHI-UHFFFAOYSA-N

Experimental research

For more information on this potential application, see Liquid breathing § Medical treatment.

Perflubron has also been tested experimentally for use in liquid breathing in premature infants with respiratory distress.^[3][4]

This molecular model of Perflubron is color-coded by electron density to illustrate the positive polarisation of the large bromine atom by the inductively electron-withdrawing perfluorooctyl chain.