Perzinfotel

Perzinfotel (EAA-090) is a drug which acts as a potent NMDA antagonist.^[1] It has neuroprotective effects and has been investigated for the treatment of stroke,^[2] but lacks analgesic effects.^[3] Nevertheless, it shows a good safety profile compared to older drugs, although further development of this drug has been discontinued.^[4]

Perzinfotel

Clinical data
ATC code	none
Identifiers
IUPAC name 2-(8,9-Dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)ethylphosphonic acid
CAS Number	144912-63-0 Y
PubChem CID	6918236
ChemSpider	5293443 N
UNII	FX5AUU7Z8T
KEGG	D05447 Y
CompTox Dashboard (EPA)	DTXSID70162846
ECHA InfoCard	100.222.780
Chemical and physical data
Formula	C9H13N2O5P
Molar mass	260.186 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CNC2=C(C(=O)C2=O)N(C1)CCP(=O)(O)O
InChI InChI=1S/C9H13N2O5P/c12-8-6-7(9(8)13)11(3-1-2-10-6)4-5-17(14,15)16/h10H,1-5H2,(H2,14,15,16) N Key:BDABGOLMYNHHTR-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Prodrugs were developed since the oral bioavailability of perzinfotel is only around 3-5%.^[5]