Pheophorbide a oxygenase

Pheophorbide a oxygenase (EC 1.14.15.17, pheide a monooxygenase, pheide a oxygenase, PAO) is an enzyme with systematic name pheophorbide-a,NADPH:oxygen oxidoreductase (biladiene-forming).^{[1][2][3][4][5][6]} This enzyme catalyses the following chemical reaction

Pheophorbide a + NADPH + H⁺ + O₂ ${\displaystyle \rightleftharpoons }$ red chlorophyll catabolite + NADP⁺

Pheophorbide a oxygenase
Identifiers
EC no.	1.14.15.17
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Pheophorbide a oxygenase participates in chlorophyll degradation. Loss-of-function mutations in the gene can lead to a stay-green phenotype in plants.^[7]