Phytoene desaturase (3,4-didehydrolycopene-forming)

Phytoene desaturase (3,4-didehydrolycopene-forming) (EC 1.3.99.30, 5-step phytoene desaturase, five-step phytoene desaturase, phytoene desaturase (ambiguous), Al-1) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming).^[1][2] This enzyme catalyses the following chemical reaction

15-cis-phytoene + 5 acceptor ${\displaystyle \rightleftharpoons }$ all-trans-3,4-didehydrolycopene + 5 reduced acceptor (overall reaction)

(1a) 15-cis-phytoene + acceptor ${\displaystyle \rightleftharpoons }$ all-trans-phytofluene + reduced acceptor

(1b) all-trans-phytofluene + acceptor ${\displaystyle \rightleftharpoons }$ all-trans-zeta-carotene + reduced acceptor

(1c) all-trans-zeta-carotene + acceptor ${\displaystyle \rightleftharpoons }$ all-trans-neurosporene + reduced acceptor

(1d) all-trans-neurosporene + acceptor ${\displaystyle \rightleftharpoons }$ all-trans-lycopene + reduced acceptor

(1e) all-trans-lycopene + acceptor ${\displaystyle \rightleftharpoons }$ all-trans-3,4-didehydrolycopene + reduced acceptor

Phytoene desaturase (3,4-didehydrolycopene-forming)
Identifiers
EC no.	1.3.99.30
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme is involved in carotenoid biosynthesis.

See also

• Phytoene desaturase (lycopene-forming)
• Phytoene desaturase (neurosporene-forming)
• Phytoene desaturase (zeta-carotene-forming)
• 15-Cis-phytoene desaturase