Pitrilysin

Pitrilysin (EC 3.4.24.55, Escherichia coli protease III, protease Pi, proteinase Pi, PTR, Escherichia coli metalloproteinase Pi) is an enzyme.^{[1][2][3][4][5]} This enzyme catalyses the following chemical reaction:

Preferential cleavage of -Tyr¹⁶- Leu- and -Phe²⁵- Tyr-bonds of oxidized insulin B chain. Also acts on other substrates of less than 7 kDa such as glucagon

Pitrilysin
Identifiers
EC no.	3.4.24.55
CAS no.	81611-78-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme is present in bacteria Escherichia coli.