Postcibalome

Postcibalome is the comprehensive array of biochemical and physiological responses that occur in the body, most notably in the blood, following the consumption of food.^[1] This term encompasses the complex interplay of hormonal, nutritional, and metabolic changes that take place as the body processes food and returns to its fasting state.^{[citation needed]} It includes fluctuations in hormones, nutrients, metabolites, and proteins, as well as stress responses associated with excessive food intake. The term "postcibalome" is derived from "postcibal," which combines the prefix "post-" (after) with the Latin word "cibus," meaning food.^{[citation needed]}

The changes in blood composition after eating are intricate and can serve as important indicators of metabolic health.^[2] Studies have shown that alterations in glucose and insulin levels are significant markers of metabolic dysfunction, with insulin resistance often signifying a risk for diabetes.^[3][4] Additionally, the gene expression and proteome of white blood cells, as well as the metabolome and proteome of the blood, exhibit dynamic changes in response to food intake.^{[citation needed]} These collective fluctuations highlight the body's adaptive mechanisms in managing nutrient intake and maintaining metabolic balance.^{[citation needed]}