Prednimustine

Prednimustine
Clinical data
Trade names	Mostarina, Sterecyst
Other names	EORTC 1502; Leo 1031; NSC 134087; Prednisolone 21-(4-(4-(bis(2-chloroethyl)-amino)phenyl)butanoate); 11β,17α-Dihydroxy-3,20-dioxopregna-1,4-dien-21-yl 4-{4-[bis(2-chloroethyl)amino]-phenyl}butanoate
ATC code	L01AA08 (WHO) ;
Identifiers
	IUPAC name [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate;
CAS Number	29069-24-7 ;
PubChem CID	34457;
ChemSpider	31708 ;
UNII	9403SIO2S8;
KEGG	C19512 ;
CompTox Dashboard (EPA)	DTXSID4021183 ;
ECHA InfoCard	100.044.904
Chemical and physical data
Formula	C35H45Cl2NO6
Molar mass	646.65 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)COC(=O)CCCc4ccc(cc4)N(CCCl)CCCl)O)CCC5=CC(=O)C=C[C@]35C)O;
	InChI InChI=1S/C35H45Cl2NO6/c1-33-14-12-26(39)20-24(33)8-11-27-28-13-15-35(43,34(28,2)21-29(40)32(27)33)30(41)22-44-31(42)5-3-4-23-6-9-25(10-7-23)38(18-16-36)19-17-37/h6-7,9-10,12,14,20,27-29,32,40,43H,3-5,8,11,13,15-19,21-22H2,1-2H3/t27-,28-,29-,32+,33-,34-,35-/m0/s1 ; Key:HFVNWDWLWUCIHC-GUPDPFMOSA-N ;
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Prednimustine, sold under the brand names Mostarina and Sterecyst, is a medication which is used in chemotherapy in the treatment of leukemias and lymphomas.^[1]^[2]^[3] It is the ester formed from two other drugs, prednisolone and chlorambucil.^[1]^[2]^[3] Rarely, it has been associated with myoclonus.^[4]

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