Prion pseudoknot

The prion pseudoknot is predicted RNA pseudoknot structure found in prion protein mRNA.^[1] It has been suggested that this element has a possible effect in prion protein translation.^[2] The human prion protein gene contains 5 copies of a 24 nucleotide repeat that contains this structure.^[2] The number of nucleotide repeats found in an organism may vary from one organism to another. Each species has a set number of nucleotide repeats, but when the organism deviates from this number, mutations in the prion genes may arise.^[2] Human individuals that exhibit these mutations may be prone to developing prion diseases, such as Creutzfeldt-Jakob disease.^[2]

Prion pseudoknot
Predicted secondary structure and sequence conservation of Prion_pknot
Identifiers
Symbol	Prion_pknot
Rfam	RF00523
Other data
RNA type	Cis-reg
Domain(s)	Eukaryota
SO	SO:0000233
PDB structures	PDBe