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Proglumetacin

Non-steroidal anti-inflammatory drug From Wikipedia, the free encyclopedia

Proglumetacin
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Proglumetacin (usually supplied as the maleate salt) is a nonsteroidal anti-inflammatory drug (NSAID). It is a codrug (that is, a mutual prodrug) of indometacin and proglumide[1]. After oral intake, it is absorbed and metabolized to indometacin and proglumide. These two substances are then released into the system in a 1:1 molar ratio.

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Indometacin contributes to the anti-inflammatory effect, while proglumide has antisecretory effects that helps prevent injury to the stomach lining.

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