Propanediol-phosphate dehydrogenase

In enzymology, a propanediol-phosphate dehydrogenase (EC 1.1.1.7) is an enzyme that catalyzes the chemical reaction

Propanediol 1-phosphate

+ NAD⁺

 

 

 

H⁺

 

H⁺

 

Hydroxyacetone phosphate

+ NADH

 

propanediol-phosphate dehydrogenase
Identifiers
EC no.	1.1.1.7
CAS no.	9028-15-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD⁺. Its products are hydroxyacetone phosphate, nicotinamide adenine dinucleotide (NADH), and a proton.^[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is propane-1,2-diol-1-phosphate:NAD⁺ oxidoreductase. Other names in common use include PDP dehydrogenase, 1,2-propanediol-1-phosphate:NAD⁺ oxidoreductase, and propanediol phosphate dehydrogenase.