Protein Local Optimization Program

Protein Local Optimization Program (PLOP) is computer software,^[3] a molecular dynamics simulation package written in the programming language Fortran. It was developed originally by Matthew P. Jacobson and Richard A. Friesner of the Friesner lab at Columbia University, and then moved to the Jacobson lab at University of California, San Francisco (UCSF), and Schrödinger, LLC.

Protein Local Optimization Program

Original author(s)	Matthew P. Jacobson, Richard A. Friesner
Developer(s)	University of California, San Francisco, Schrödinger
Initial release	2000; 25 years ago (2000)
Stable release	Schrödinger Release 2016-4[1] / April 2016; 9 years ago (2016-04)
Written in	Fortran
Operating system	Unix-like
Available in	English
Type	Molecular mechanics
License	Proprietary commercial, academic freeware[2]
Website	wiki.jacobsonlab.org

See also

• Comparison of software for molecular mechanics modeling