Protein phosphatase methylesterase-1

The enzyme protein phosphatase methylesterase-1 (EC 3.1.1.89, PME-1, PPME1; systematic name (phosphatase 2A protein)-leucine ester acylhydrolase^[1][2] catalyses the reaction

[phosphatase 2A protein]-leucine methyl ester + H₂O ${\displaystyle \rightleftharpoons }$ [phosphatase 2A protein]-leucine + methanol

Protein phosphatase methylesterase-1
Identifiers
EC no.	3.1.1.89
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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A key regulator of protein phosphatase 2A.