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Protoporphyrinogen IX dehydrogenase (menaquinone)

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Protoporphyrinogen IX dehydrogenase (menaquinone) (EC 1.3.5.3, HemG) is an enzyme with systematic name protoporphyrinogen IX:menaquinone oxidoreductase.[1] This enzyme catalyses the following chemical reaction

protoporphyrinogen IX + 3 menaquinone protoporphyrin IX + 3 menaquinol

This enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments.

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