Pseudomonas sRNA P16

Pseudomonas sRNA P16 is a ncRNA that was predicted using bioinformatic tools in the genome of the opportunistic pathogen Pseudomonas aeruginosa and its expression verified by northern blot analysis.^[1] P16 sRNA appears to be conserved across several Pseudomonas species and is consistently located downstream of a predicted TatD deoxyribonuclease gene. P16 has a predicted Rho independent terminator at the 3′ end but the function of P16 is unknown.^[1]

Pseudomonas sRNA P16
Predicted secondary structure and sequence conservation of P16
Identifiers
Symbol	P16
Rfam	RF00628
Other data
RNA type	Gene
Domain	Bacteria
SO	SO:0000655
PDB structures	PDBe

It has been shown that this sRNA is transcribed from an RpoS-dependent promoter under positive, probably indirect GacA control in two Pseudomonas species. It was renamed RgsA (for regulation by GacA and stress).^[2] RpoS mRNA expression is repressed by RgsA during the exponential phase. The Hfq RNA chaperone is required for the repression.^[3]

See also

• Pseudomonas sRNA P1
• Pseudomonas sRNA P9
• Pseudomonas sRNA P11
• Pseudomonas sRNA P15
• Pseudomonas sRNA P24
• Pseudomonas sRNA P26