Pyr-AI

Pyr-AI, also known as 2-pyrrolidinylindane (2-PYI), is a stimulant drug of the 2-aminoindane family.^[1] It is the analogue of 2-aminoindane (2-AI) in which the amine has been replaced with a pyrrolidine group.^[1] The drug has been described as having strong and long-lasting amphetamine-like effects in rodents.^[1][2] Other 2-aminoindanes like 2-AI itself and NM-2-AI are known to act as potent monoamine releasing agents and reuptake inhibitors.^[3][4] Pyr-AI was first described in the scientific literature by 1973.^[1][2]

Pyr-AI

Clinical data
Other names	2-PYI; 2-Pyrrolidinylindane; 1-(2-Indanyl)pyrrolidine; Compound 10j
Drug class	Stimulant
ATC code	None
Identifiers
IUPAC name 1-(2,3-dihydro-1H-inden-2-yl)pyrrolidine
CAS Number	43152-60-9
PubChem CID	206203
ChemSpider	178662
CompTox Dashboard (EPA)	DTXSID60195729
Chemical and physical data
Formula	C13H17N
Molar mass	187.286 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CCN(C1)C2CC3=CC=CC=C3C2
InChI InChI=1S/C13H17N/c1-2-6-12-10-13(9-11(12)5-1)14-7-3-4-8-14/h1-2,5-6,13H,3-4,7-10H2 Key:PAOQQDSGNKTTRU-UHFFFAOYSA-N

See also

• Substituted 2-aminoindane
• Cyclized phenethylamine
• Phenylethylpyrrolidine
• Prolintane