Pyrinuron

Pyrinuron (Pyriminil, Vacor) is a chemical compound formerly used as a rodenticide.^[1] Commercial distribution was voluntarily suspended in 1979 and it is not approved by the Environmental Protection Agency for use in the United States.^[2] If it is ingested by humans in high doses, it may selectively destroy insulin-producing beta cells in the pancreas causing type 1 diabetes.^[2] The neurodegeneration associated with Vacor is caused by its conversion to Vacor-mononucleotide (VMN) by NAMPT and VMN's subsequent activation of the NADase SARM1.^[3]

Pyrinuron

Names
Preferred IUPAC name N-(4-Nitrophenyl)-N′-[(pyridin-3-yl)methyl]urea
Other names Pyriminil Vacor
Identifiers
CAS Number	53558-25-1 Y
3D model (JSmol)	Interactive image
ChemSpider	37276 Y
ECHA InfoCard	100.053.279
PubChem CID	40813
UNII	Q7BGS137YP Y
CompTox Dashboard (EPA)	DTXSID1042360
InChI InChI=1S/C13H12N4O3/c18-13(15-9-10-2-1-7-14-8-10)16-11-3-5-12(6-4-11)17(19)20/h1-8H,9H2,(H2,15,16,18) Y Key: CLKZWXHKFXZIMA-UHFFFAOYSA-N Y InChI=1/C13H12N4O3/c18-13(15-9-10-2-1-7-14-8-10)16-11-3-5-12(6-4-11)17(19)20/h1-8H,9H2,(H2,15,16,18) Key: CLKZWXHKFXZIMA-UHFFFAOYAA
SMILES [O-][N+](=O)c1ccc(cc1)NC(=O)NCc2cccnc2
Properties
Chemical formula	C13H12N4O3
Molar mass	272.264 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Toxic
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references