Pyruvate dehydrogenase (NADP+)

Pyruvate dehydrogenase (NADP⁺) EC 1.2.1.51 is an enzyme that should not be confused with Pyruvate dehydrogenase (acetyltransferase) EC 1.2.4.1.^[1][2]

Pyruvate dehydrogenase (NADP+)
Identifiers
EC no.	1.2.1.51
CAS no.	93389-35-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

It catalyzes the following reaction:

Pyruvate + Coenzyme A + NADP⁺ ⇒ acetyl-CoA + NADPH + H⁺ + CO₂