RNA binding protein, fox-1 homolog (c. elegans) 3

RNA binding protein, fox-1 homolog (C. elegans) 3 (Rbfox3) is a protein that in humans is encoded by the RBFOX3 gene. It is related to the alternative splicing factors Rbfox1 and Rbfox2, but instead of its involvement in splicing, it is most well known as the nuclear biomarker NeuN.^{[4] [5]}

RBFOX3
Identifiers
Aliases	RBFOX3, FOX-3, FOX3, HRNBP3, NEUN, RNA binding protein, fox-1 homolog 3, uncharacterized LOC644767
External IDs	OMIM: 616999; MGI: 106368; HomoloGene: 140607; GeneCards: RBFOX3; OMA:RBFOX3 - orthologs
Gene location (Mouse) Chr. Chromosome 11 (mouse)[1] Band 11 E2|11 83.22 cM Start 118,489,762 bp[1] End 118,911,597 bp[1]
Gene ontology Molecular function DNA binding mRNA binding RNA binding nucleic acid binding Cellular component cytoplasm perikaryon soma intracellular anatomical structure nucleus Biological process regulation of RNA splicing mRNA processing regulation of alternative mRNA splicing, via spliceosome RNA splicing nervous system development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 146713 52897 Ensembl ENSG00000167281 ENSMUSG00000025576 UniProt A6NFN3 K7EJX6 Q8BIF2 RefSeq (mRNA) NM_001039904 NM_001024931 NM_001039167 NM_001039168 NM_001285436 NM_001285437 NM_001285438 RefSeq (protein) NP_001076044 NP_001337380 NP_001337382 NP_001020102 NP_001034256 NP_001034257 NP_001272365 NP_001272366 NP_001272367 Location (UCSC) n/a Chr 11: 118.49 – 118.91 Mb PubMed search [2] [3]
Wikidata
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See also

• NeuN
• Rbfox1 and Rbfox2
• Alternative splicing