RJR-2429

RJR-2429 is a drug that acts as an agonist at neural nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. RJR-2429 is stronger than nicotine but weaker than epibatidine in most assays, and with high affinity for both α3β4 and α4β2 subtypes, as well as the less studied α1βγδ subtype.^[1][2][3]

RJR-2429

Identifiers
CAS Number	91556-75-1
PubChem CID	10176454
ChemSpider	8351959
UNII	Q2L6T24QLT
CompTox Dashboard (EPA)	DTXSID40436425
Chemical and physical data
Formula	C12H16N2
Molar mass	188.274 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1(C2N(CC3)CCC3C2)=CN=CC=C1
InChI InChI=1S/C12H16N2/c1-2-11(9-13-5-1)12-8-10-3-6-14(12)7-4-10/h1-2,5,9-10,12H,3-4,6-8H2 Key:YJYPZLAZNIGNRP-UHFFFAOYSA-N