Reversine

Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation.^[1][2]

Reversine

Names
IUPAC name N′-Cyclohexyl-N-(4-morpholinophenyl)-7H-purine-2,6-diamine
Identifiers
CAS Number	656820-32-5 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:70723 N
ChemSpider	182286 N
ECHA InfoCard	100.164.070
MeSH	C484369
PubChem CID	210332
UNII	Z499CLJ023 Y
CompTox Dashboard (EPA)	DTXSID8041113
InChI InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27) N Key: ZFLJHSQHILSNCM-UHFFFAOYSA-N N InChI=1/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27) Key: ZFLJHSQHILSNCM-UHFFFAOYAD
SMILES C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
Properties
Chemical formula	C21H27N7O
Molar mass	393.495 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

It also has the potential to selectively induce cell death in cancer cells.^[3]

Reversine is known to act as an antagonist of the adenosine A₃ receptor. Reversine is a potent inhibitor of the mitotic kinase Mps1^[4] and it is widely used to study the process of chromosome segregation.