Ribonucleoside-triphosphate reductase

Ribonucleoside-triphosphate reductase (EC 1.17.4.2, ribonucleotide reductase, 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase) is an enzyme with systematic name 2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase.^[1][2][3] This enzyme catalyses the following chemical reaction

2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H₂O ${\displaystyle \rightleftharpoons }$ ribonucleoside triphosphate + thioredoxin

Ribonucleoside-triphosphate reductase
Ribonucleoside-triphosphate reductase dimer, Thermotoga maritima
Identifiers
EC no.	1.17.4.2
CAS no.	9068-66-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Ribonucleoside-triphosphate reductase requires a cobamide coenzyme and ATP.