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Ribulose 5-phosphate

Chemical compound From Wikipedia, the free encyclopedia

Ribulose 5-phosphate
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Ribulose 5-phosphate is one of the end-products of the pentose phosphate pathway. It is also an intermediate in the Calvin cycle.

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It is formed by phosphogluconate dehydrogenase in the pentose phosphate pathway.[2][3] Ribulose 5-phosphate is involved in various metabolic pathways. Ribulose 5-phosphate can be acted upon by phosphopentose isomerase to form ribose 5-phosphate, which is a precursor for nucleotide and co-factor biosynthesis.[2] Ribulose-5 phosphate can also be acted upon by phosphopentose epimerase to form xylulose 5-phosphate, which is used in the nonoxidative phase of the pentose phosphate pathway in humans to generate precursor molecules for the synthesis of aromatic amino acids and production of energy.[3]

In plants, ribulose 5-phosphate produced from the pentose-phosphate pathway is converted into ribulose-1,5-bisphosphate by the enzyme phosphoribokinase.

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