Ro5-3335

Ro5-3335 is an experimental drug from the benzodiazepine family which acts as a selective inhibitor of the protein Runt-related transcription factor 1 (RUNX1). Inhibition of this protein is useful in numerous medical applications, and Ro5-3335 has beneficial effects against diverse conditions including HIV infection, leukemia and some other forms of cancer, recovery following heart attack, acute kidney injury, and some types of retinopathy.^{[1][2][3][4][5][6][7][8][9]}

Ro5-3335

Identifiers
IUPAC name 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number	30195-30-3
PubChem CID	64983
ChemSpider	58508
UNII	DLH4T68L7I
ChEBI	CHEBI:131785
ChEMBL	ChEMBL91609
CompTox Dashboard (EPA)	DTXSID20184270
Chemical and physical data
Formula	C13H10ClN3O
Molar mass	259.69 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CN3
InChI InChI=1S/C13H10ClN3O/c14-8-3-4-10-9(6-8)13(11-2-1-5-15-11)16-7-12(18)17-10/h1-6,15H,7H2,(H,17,18) Key:XWNMORIHKRROGW-UHFFFAOYSA-N