Ruberlysin

Ruberlysin (EC 3.4.24.48, Crotalus ruber metalloendopeptidase II, hemorrhagic toxin II) is an enzyme.^[1][2] This enzyme catalyses the following chemical reaction

Cleavage of His¹⁰-Leu, Ala¹⁴-Leu, Tyr¹⁶-Leu and Gly²³-Phe bonds in the B chain of insulin; His-Pro, Pro-Phe, and Trp-Ser of angiotensin I; and Gly-Phe of Met enkephalin

Ruberlysin
Identifiers
EC no.	3.4.24.48
CAS no.	846020-01-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This endopeptidase is present in the venom of the red rattlesnake (Crotalus ruber ruber).