Ruplizumab

Ruplizumab (trade name Antova) is a humanized monoclonal antibody intended for the treatment of rheumatic diseases like systemic lupus erythematosus and lupus nephritis. A study showed that the drug was associated with life-threatening thromboembolisms,^[1] while another study only found thrombocytopenia.^[2]

Ruplizumab

Monoclonal antibody
Type	Whole antibody
Source	Humanized (from mouse)
Target	CD154
Clinical data
Trade names	Antova
ATC code	none
Identifiers
CAS Number	220651-94-5 N
ChemSpider	none
UNII	562JQF15GN
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