Anion exchange transporter

Anion exchange transporter is a protein that in humans is encoded by the SLC26A7 gene.^[5][6][7][8]

SLC26A7
Identifiers
Aliases	SLC26A7, SUT2, solute carrier family 26 member 7
External IDs	OMIM: 608479; MGI: 2384791; HomoloGene: 13770; GeneCards: SLC26A7; OMA:SLC26A7 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q21.3 Start 91,209,494 bp[1] End 91,398,155 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 A1 Start 14,502,430 bp[2] End 14,621,805 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in thyroid gland right lobe of thyroid gland left lobe of thyroid gland retinal pigment epithelium renal medulla human kidney testicle endometrium lymph node placenta Top expressed in vestibular membrane of cochlear duct retinal pigment epithelium ciliary body iris olfactory epithelium renal corpuscle vestibular sensory epithelium pineal gland lumbar spinal ganglion molar More reference expression data BioGPS n/a
Gene ontology Molecular function anion channel activity anion transmembrane transporter activity sulfate transmembrane transporter activity secondary active sulfate transmembrane transporter activity bicarbonate transmembrane transporter activity oxalate transmembrane transporter activity chloride channel activity chloride transmembrane transporter activity Cellular component cytoplasm integral component of membrane endosome membrane plasma membrane integral component of plasma membrane recycling endosome membrane basolateral plasma membrane Biological process oxalate transport sulfate transport gastric acid secretion regulation of membrane potential regulation of intracellular pH ion transport anion transport bicarbonate transport chloride transport chloride transmembrane transport anion transmembrane transport sulfate transmembrane transport transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 115111 208890 Ensembl ENSG00000147606 ENSMUSG00000040569 UniProt Q8TE54 Q8R2Z3 RefSeq (mRNA) NM_134266 NM_001282356 NM_001282357 NM_052832 NM_145947 RefSeq (protein) NP_001269285 NP_001269286 NP_439897 NP_599028 NP_666059 Location (UCSC) Chr 8: 91.21 – 91.4 Mb Chr 4: 14.5 – 14.62 Mb PubMed search [3] [4]
Wikidata
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Function

This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Splice variants that use both alternate transcription initiation and polyadenylation sites have been described for this gene.^[8]

See also

• Solute carrier family