Neutral and basic amino acid transport protein rBAT

Neutral and basic amino acid transport protein rBAT is a protein that in humans is encoded by the SLC3A1 gene.^[5][6][7]

SLC3A1
Identifiers
Aliases	SLC3A1, ATR1, CSNU1, D2H, NBAT, RBAT, solute carrier family 3 member 1
External IDs	OMIM: 104614; MGI: 1195264; HomoloGene: 37289; GeneCards: SLC3A1; OMA:SLC3A1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p21 Start 44,275,458 bp[1] End 44,321,494 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 E4|17 55.17 cM Start 85,335,804 bp[2] End 85,371,664 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas gallbladder islet of Langerhans human kidney mucosa of transverse colon rectum oocyte testicle secondary oocyte duodenum Top expressed in right kidney proximal tubule human kidney jejunum ileum proximal straight tubule left lobe of liver intestinal epithelium duodenum intestinal villus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity L-cystine transmembrane transporter activity catalytic activity protein binding protein heterodimerization activity Cellular component integral component of membrane membrane vacuolar membrane plasma membrane integral component of plasma membrane brush border membrane mitochondrial inner membrane extracellular exosome Biological process cellular amino acid metabolic process basic amino acid transport amino acid transport L-cystine transport amino acid transmembrane transport basic amino acid transmembrane transport transport carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6519 20532 Ensembl ENSG00000138079 ENSMUSG00000024131 UniProt Q07837 Q91WV7 RefSeq (mRNA) NM_000341 NM_009205 RefSeq (protein) NP_000332 NP_033231 Location (UCSC) Chr 2: 44.28 – 44.32 Mb Chr 17: 85.34 – 85.37 Mb PubMed search [3] [4]
Wikidata
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Mutations in the SLC3A1 gene are associated with cystinuria.

See also

• Heterodimeric amino acid transporter
• Solute carrier family