High affinity cationic amino acid transporter 1

High affinity cationic amino acid transporter 1 is a protein that in humans is encoded by the SLC7A1 gene.^[5][6]

SLC7A1
Identifiers
Aliases	SLC7A1, ATRC1, CAT-1, ERR, HCAT1, REC1L, solute carrier family 7 member 1
External IDs	OMIM: 104615; MGI: 88117; HomoloGene: 20658; GeneCards: SLC7A1; OMA:SLC7A1 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q12.3 Start 29,509,414 bp[1] End 29,595,688 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 G3|5 88.48 cM Start 148,264,220 bp[2] End 148,336,714 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gums gingival epithelium endothelial cell buccal mucosa cell parotid gland mucosa of pharynx oral cavity corpus epididymis Epithelium of choroid plexus dorsal motor nucleus of vagus nerve Top expressed in cumulus cell lacrimal gland utricle Paneth cell hair follicle condyle conjunctival fornix endothelial cell of lymphatic vessel seminal vesicula facial motor nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding amino acid transmembrane transporter activity L-ornithine transmembrane transporter activity L-lysine transmembrane transporter activity transmembrane transporter activity Cellular component integral component of membrane integral component of plasma membrane membrane plasma membrane protein-containing complex Biological process amino acid transmembrane transport L-arginine transmembrane transport amino acid transport transport transmembrane transport L-arginine import across plasma membrane L-ornithine transmembrane transport L-lysine transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6541 11987 Ensembl ENSG00000139514 ENSMUSG00000041313 UniProt P30825 Q09143 RefSeq (mRNA) NM_003045 NM_001301424 NM_007513 RefSeq (protein) NP_003036 NP_001288353 NP_031539 Location (UCSC) Chr 13: 29.51 – 29.6 Mb Chr 5: 148.26 – 148.34 Mb PubMed search [3] [4]
Wikidata
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See also

• Solute carrier family