Cationic amino acid transporter 2

Cationic amino acid transporter 2 is a protein that in humans is encoded by the SLC7A2 gene.^[5][6]

SLC7A2
Identifiers
Aliases	SLC7A2, ATRC2, CAT2, HCAT2, solute carrier family 7 member 2
External IDs	OMIM: 601872; MGI: 99828; HomoloGene: 20659; GeneCards: SLC7A2; OMA:SLC7A2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8p22 Start 17,497,088 bp[1] End 17,570,573 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8 A4|8 23.89 cM Start 41,315,433 bp[2] End 41,375,345 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Skeletal muscle tissue of rectus abdominis biceps brachii Skeletal muscle tissue of biceps brachii islet of Langerhans right lobe of liver trigeminal ganglion gastrocnemius muscle bronchial epithelial cell retinal pigment epithelium right ovary Top expressed in epithelium of lens Dermatocranium membranous bone left lobe of liver mandible maxilla muscle of thigh secondary oocyte islet of Langerhans ciliary body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function high-affinity lysine transmembrane transporter activity low-affinity L-arginine transmembrane transporter activity L-arginine transmembrane transporter activity basic amino acid transmembrane transporter activity high-affinity L-arginine transmembrane transporter activity high-affinity L-ornithine transmembrane transporter activity L-ornithine transmembrane transporter activity L-lysine transmembrane transporter activity amino acid transmembrane transporter activity transmembrane transporter activity Cellular component integral component of membrane membrane integral component of plasma membrane plasma membrane cell junction Biological process nitric oxide biosynthetic process cellular amino acid metabolic process nitric oxide production involved in inflammatory response regulation of inflammatory response L-lysine import across plasma membrane L-arginine import across plasma membrane L-ornithine import across plasma membrane macrophage activation L-ornithine transmembrane transport amino acid transport regulation of macrophage activation transmembrane transport L-lysine transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6542 11988 Ensembl ENSG00000003989 ENSMUSG00000031596 UniProt P52569 P18581 RefSeq (mRNA) NM_001008539 NM_001164771 NM_003046 NM_001370337 NM_001370338 NM_001044740 NM_007514 RefSeq (protein) NP_001008539 NP_001158243 NP_003037 NP_001357266 NP_001357267 NP_001038205 NP_031540 Location (UCSC) Chr 8: 17.5 – 17.57 Mb Chr 8: 41.32 – 41.38 Mb PubMed search [3] [4]
Wikidata
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See also

• SLC7A2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)