Sodium–hydrogen antiporter 2

Sodium–hydrogen exchanger 2 is a protein that in humans is encoded by the SLC9A2 gene.^[5]

SLC9A2
Identifiers
Aliases	SLC9A2, NHE2, solute carrier family 9 member A2
External IDs	OMIM: 600530; MGI: 105075; HomoloGene: 20661; GeneCards: SLC9A2; OMA:SLC9A2 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q12.1 Start 102,619,553 bp[1] End 102,711,355 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 B|1 19.66 cM Start 40,719,734 bp[2] End 40,808,433 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in rectum testicle mucosa of transverse colon mucosa of sigmoid colon buccal mucosa cell pylorus muscle of thigh body of stomach epithelium of colon gastrocnemius muscle Top expressed in interventricular septum left colon jejunum prostate epithelium of stomach seminal vesicula lobe of prostate extraocular muscle duodenum sternocleidomastoid muscle More reference expression data BioGPS n/a
Gene ontology Molecular function solute:proton antiporter activity antiporter activity potassium:proton antiporter activity sodium:proton antiporter activity Cellular component integral component of membrane membrane plasma membrane Biological process proton transmembrane transport protein localization cation transport ion transport regulation of pH sodium ion transport regulation of intracellular pH sodium ion import across plasma membrane potassium ion transmembrane transport transmembrane transport anion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6549 226999 Ensembl ENSG00000115616 ENSMUSG00000026062 UniProt Q9UBY0 n/a RefSeq (mRNA) NM_003048 NM_001033289 RefSeq (protein) NP_003039 n/a Location (UCSC) Chr 2: 102.62 – 102.71 Mb Chr 1: 40.72 – 40.81 Mb PubMed search [3] [4]
Wikidata
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See also

• Solute carrier family