SLiM

SLiM ("Selection on Linked Mutations") is software designed for conducting forward-in-time genetic simulations of eco-evolutionary scenarios. It allows researchers to simulate complex population genetics models, accommodating both Wright-Fisher and non-Wright-Fisher models. Over a thousand scientific papers have cited one of the SLiM release publications (and, presumably, used the software for simulations), according to GoogleScholar (in particular version 3^[1]).

SLiM supports various evolutionary processes, including mutation, recombination, migration, and genetic drift,^[2] selection on fecundity or survival,^[3] and is designed to enable users to explore the dynamics of genomes under different selective pressures and demographic events of one or multiple populations and species.^[4]

The SLiM also offers a scripting language, Eidos, which provides customization options for defining evolutionary parameters and interactions within and between populations. Almost all information regarding Eidos and SLiM are available in the SLiM^[5] and Eidos manuals.^[6]